Human Matriptase / ST14 Catalytic Domain Protein, Tag Free (active enzyme)
Degrades extracellular matrix. Proposed to play a role in breast cancer invasion and metastasis. Exhibits trypsin-like activity as defined by cleavage of synthetic substrates with Arg or Lys as the P1 site. Involved in the terminal differentiation of keratinocytes through prostasin (PRSS8) activation and filaggrin (FLG) processing; Cleaves various synthetic substrates with Arg or Lys at the P1 position and prefers small side-chain amino acids, such as Ala and Gly, at the P2 position.
Product Specifications
Background
Specifications
Accession Number
NP_068813
Expression Region
Gly 596 - Val 855
Host
E. coli
Target
Matriptase
Conjugation
Unconjugated
Tag
Native
Source
Human
Stability
The product MUST be stored at -70°C or lower upon receipt; -70°C for 3 months under sterile conditions.
Endotoxin
1.0 EU per μg
Purity
90%
Format
Liquid
Buffer
50 mM Tris, 150 mM NaCl, 10 % Trehalose, pH7.5
Additives
Glycerol
Molecular Weight
30.6 kDa
Additionnal Information
Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments
Shipping Conditions
Dry ice
Storage Conditions
-70°C
Package Size
1mg*1
Host or Source
E. coli
Species
Human
Protein ID
NP_068813
Preservative
Glycerol
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