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GMP Human IL-1 beta Protein

Interleukin-1 beta (IL-1β) is a non-secreted proinflammatory cytokine produced mainly by activated macrophages, as well as neutrophils, epithelial cells, and endothelial cells. It possesses metabolic, physiological, haematopoietic activities, and plays one of the central roles in the regulation of the immune responses. Both IL-1α and IL-1β binds to the same receptor and has similar but not identical biological properties; The mature human IL1β shares 96 % amino acid sequence identity with rhesus and 67 % -78 % with canine, mouse and rat IL-1β.

Product Specifications

Background

Interleukin-1 beta (IL-1β) is a non-secreted proinflammatory cytokine produced mainly by activated macrophages, as well as neutrophils, epithelial cells, and endothelial cells. It possesses metabolic, physiological, haematopoietic activities, and plays one of the central roles in the regulation of the immune responses. Both IL-1α and IL-1β binds to the same receptor and has similar but not identical biological properties; The mature human IL1β shares 96 % amino acid sequence identity with rhesus and 67 % -78 % with canine, mouse and rat IL-1β.

Specifications

This protein carries no "tag". The protein has a calculated MW of 17.5 kDa. The protein migrates as 18 kDa±3 kDa under reducing (R) condition (SDS-PAGE) .

Accession Number

P01584-1

Expression Region

Ala 117 - Ser 269

Host

E. coli

Target

IL-1 beta

Conjugation

Unconjugated

Tag

Native

Source

Human

Stability

-20°C to -70°C for 5 years in lyophilized state; -70°C for 12 months under sterile conditions after reconstitution. Upon receipt, store it immediately at -20°C or lower for long term storage.

Endotoxin

10 EU/mg

Purity

95%

Format

Powder-GMP

Buffer

PBS, pH7.4

Molecular Weight

17.5 kDa

Additionnal Information

Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments

Shipping Conditions

Blue ice

Storage Conditions

-20°C

Package Size

50ug*20

Host or Source

E. coli

Species

Human

Protein ID

P01584-1

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