Cynomolgus TROP-2 / TACSTD2 Protein, His Tag (MALS verified)
Cynomolgus TROP-2 Protein, His Tag (TR2-C52H5) is expressed from human 293 cells (HEK293) . It contains AA Gln 31 - Thr 274 (Accession # XP_005543292.2) .
Product Specifications
Background
TROP-2 is a single-copy gene in human cells, and encodes a type-1 transmembrane glycoprotein which is over-expressed in various malignancies, also referred to as tumor associated calcium signal transducer 2 (TACSTD2), GA733-1 or M1S1. TROP-2 is related to epithelial cell adhesion molecule (EpCAM), also called TROP-1, gp40, and KSA. Trop-1 and Trop-2 are homologous to serum IGF-II-binding proteins and appear as signal transducers. Thus, they likely represent novel cell-surface receptors and may play a role in regulating the growth of carcinoma cells.
Specifications
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 29.4 kDa. The protein migrates as 40-53 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Accession Number
XP_005543292.2
Expression Region
Gln 31 - Thr 274
Host
HEK293
Target
TROP-2
Conjugation
Unconjugated
Tag
C-10xHis
Source
Cynomolgus
Stability
● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Endotoxin
1.0 EU per μg
Purity
90%
Bioactivity
Immobilized Cynomolgus TROP-2 Protein, His Tag (Cat. No. TR2-C52H5) at 1 μg/mL (100 μL/well) can bind Mouse Monoclonal Antibody Against Human TROP-2 Protein,Mouse IgG1 with a linear range of 0.1-2 ng/mL (QC tested).
Format
Powder
Buffer
PBS, pH7.4
Additives
Trehalose
Molecular Weight
29.4 kDa
Shipping Conditions
RT
Storage Conditions
-20°C
Package Size
100ug*1
Product Datasheet
Https://www.acrobiosystems.com/static/main/products/pdf/ds/TR2-C52H5.pdf
Species
Cynomolgus
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