Biotinylated Human HLA-E*01:03&B2M&CMV UL40 (VMAPRTVIL) Complex Protein (Monomer, MALS verified)
HLA-E belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin) . The heavy chain is anchored in the membrane. HLA-E binds a restricted subset of peptides derived from the leader peptides of other class I molecules. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail.
Product Specifications
Background
Specifications
Accession Number
P13747 (HLA-E*01:03) & P61769-1 (B2M) & VMAPRTVIL
Expression Region
Gly 22 - Ile 305 (HLA-E*01:03) & Ile 21 - Met 119 (B2M) & VMAPRTVIL peptide
Host
HEK293
Target
HLA-E*0103 & B2M & CMV UL40 (VMAPRTVIL)
Conjugation
Biotin-labeled
Tag
C-10xHis & C-Avi
Source
Human
Stability
Endotoxin
1.0 EU per μg
Purity
95%
Format
Powder
Buffer
PBS, pH7.4
Additives
Trehalose
Molecular Weight
36.2 kDa and 13.7 kDa
Additionnal Information
Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments
Shipping Conditions
RT
Storage Conditions
-20°C
Package Size
200ug*1
Host or Source
HEK293
Species
Human
Protein ID
P13747 (HLA-E*01:03) & P61769-1 (B2M) & VMAPRTVIL
Preservative
Trehalose
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