HSV-1 (strain KOS) post-gB Protein, His Tag (MALS verified)

Herpes simplex viruses (HSV) -1 and HSV-2 cause a variety of human diseases, including encephalitis, keratitis, neonatal disease, and mucocutaneous and skin diseases such as herpes labialis, genital herpes, and herpetic whitlow. HSV-1 gB, which is a class III fusion glycoprotein, is a major target of antibody-mediated immunity (21) . It plays an essential role in the entry of the virus into a host cell, together with other HSV-1 envelope glycoproteins, including gD and a complex of gH and gL (gH/gL) .

Product Specifications

Background

Specifications

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 73.5 kDa. The protein migrates as 80-95 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

Accession Number

P06437

Expression Region

Asp 103 - Ala 730

Host

HEK293

Target

Postfusion glycoprotein B/Postfusion gB (HSV)

Conjugation

Unconjugated

Tag

C-10xHis

Source

HSV-1

Stability

-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Endotoxin

1.0 EU per μg

Purity

90%

Bioactivity

Immobilized HSV-1 (strain KOS) post-gB Protein, His Tag (Cat. No. POB-V52H3) at 1 μg/mL (100 μL/well) can bind Mouse anti-Herpes virus 1 and2,clone T111(Monoclonal) (Cat. No. SPN-C524u) with a linear range of 0.06-1 ng/mL (QC tested).