Human FGF-17 Protein, His Tag (HPLC verified)

Fibroblast growth factors (FGFs) are a large family of structurally related proteins that are involved in wide variety of cellular processes including proliferation, differentiation, migration, and apoptosis. FGF17 also referred to as FGF-13, is expressed during embryogenesis and in the adult cerebellum and cortex and may be essential for vascular growth and normal brain development. Additionally, FGF17 together with FGF8, is a key factor in the patterning of the mid-hindbrain region with a complex picture of spatiotemporal gene expression during the various stages of cerebellar development.

This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 24.5 kDa. The protein migrates as 28-30 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under non-reducing (NR) condition (SDS-PAGE) .

● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Immobilized Human FGF-17 Protein, His Tag (Cat. No. FG7-H5144) at 5 μg/mL (100 μL/well) can bind Human FGF R3 (IIIc), Fc Tag (Cat. No. FGC-H5256) with a linear range of 2-40 ng/mL (QC tested).