HsTx1
HsTx-1 is a member of the a-KTx6 family of scorpion toxins active on voltage-gated Kv1.3 channels (Kd close to 10 pM) . HsTx-1 is also very active on Kv1.1 channels (IC50 around 7 nM) . It is however inactive on apamin-sensitive SK channels. It is one of the most potent toxins active on Kv1.3 channel.
Product Specifications
Specifications
Selective blocker of Kv1.3 channel
Target
K channels
Sequence
ASCRTPKDCADPCRKETGCPYGKCMNRKCKCNRC
Peptide Number
08NEU001
Disulfide Bonds
Cys3-Cys24; Cys9-Cys29; Cys13-Cys31; Cys19-Cys34
N Terminal Sequence
H
C Terminal Sequence
NH2
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