SRF-RE Luciferase Reporter-HEK293 Cell Line

The SRF-RE Luciferase Reporter cell line is a stably transfected HEK 293 cell line which expresses Renilla luciferase reporter gene under the transcriptional control of the serum response factor-response element (SRF-RE) . The SRF-RE reporter cell line can be used for studying GPCR-linked RhoA signaling pathways as well as screening of agonists, antagonists or signaling inhibitors related with the RhoA signaling pathways. Functional activity of the cell line has been validated by serum stimulation assay (Figure 1) .