What is the catalog number for BBT594?

The catalog number for BBT594 is HY-18840.

What sizes are available for BBT594?

BBT594 is available in the following size(s): 5 mg, 10 mM - 1 mL, 10 mg, 50 mg, 100 mg.

How many pack sizes does BBT594 come in?

BBT594 is available in 5 different pack sizes.

BBT594 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures BBT594?

BBT594 is manufactured by QuantiMol.

What is the estimated delivery time for BBT594?

Estimated delivery time for BBT594 is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for BBT594?

The safety data sheet for BBT594 is available here: http://file.medchemexpress.com/batch_PDF/HY-18840/BBT594-SDS-MedChemExpress.pdf.

BBT594

BBT594 is a potent receptor tyrosine kinase RET inhibitor, used for cancer treatment.

Product Specifications

CAS Number

882405-89-2

Product Name Alternative

NVP-BBT594

UNSPSC

12352005

Hazard Statement

H315, H317, H318, H334, H335, H341, H361, H370, H413

Target

RET

Type

Reference compound

Related Pathways

Protein Tyrosine Kinase/RTK

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/BBT594.html

Concentration

10mM

Purity

99.81

Solubility

DMSO : ≥ 33 mg/mL

Smiles

O=C(N1CCC2=C1C=CC(OC3=NC=NC(NC(C)=O)=C3)=C2)NC4=CC=C(CN5CCN(C)CC5)C(C(F)(F)F)=C4

Molecular Formula

C28H30F3N7O3

Molecular Weight

569.58

Precautions

H315, H317, H318, H334, H335, H341, H361, H370, H413

References & Citations

[1]Morandi A, et al. GDNF-RET signaling in ER-positive breast cancers is a key determinant of response and resistance to aromatase inhibitors. Cancer Res. 2013 Jun 15;73 (12) :3783-95|[2]Andreucci E, et al. Targeting the receptor tyrosine kinase RET in combination with aromatase inhibitors in ER positive breast cancer xenografts. Oncotarget. 2016 Sep 2. doi: 10.18632/oncotarget.11826. [Epub ahead of print]