Idazoxan (hydrochloride)
Idazoxan hydrochloride (RX 781094 hydrochloride) is an α2-adrenoceptor antagonist and is also a imidazoline receptors (IRs) antagonist competitively antagonized the centrally induced hypotensive effect of imidazoline-like agents (IMs) . Idazoxan hydrochloride also improves motor symptoms in Parkinson’s disease, L-DOPA-induced dyskinesias, and experimental Parkinsonism[1][2].
Product Specifications
CAS Number
79944-56-2
Product Name Alternative
RX 781094 (hydrochloride)
UNSPSC
12352005
Hazard Statement
H301
Target
Adrenergic Receptor; Imidazoline Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Neurological Disease; Endocrinology
Assay Protocol
https://www.medchemexpress.com/idazoxan-hydrochloride.html
Purity
99.32
Solubility
DMSO : 116.67 mg/mL (ultrasonic) |H2O : 100 mg/mL (ultrasonic)
Smiles
[H]Cl.C1(C2OC3=CC=CC=C3OC2)=NCCN1
Molecular Formula
C11H13ClN2O2
Molecular Weight
240.69
Precautions
H301
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
Phase 3
Isoform
α adrenergic receptor
Available Sizes
Frequently Asked Questions
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