Venlafaxine
Venlafaxine (Wy 45030) is an orally active, potent serotonin (5-HT) /norepinephrine (NE) reuptake dual inhibitor. Venlafaxine is an antidepressant[1].
Product Specifications
CAS Number
93413-69-5
Product Name Alternative
Wy 45030
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Serotonin Transporter
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease; Cancer
Assay Protocol
https://www.medchemexpress.com/venlafaxine.html
Purity
99.94
Solubility
DMSO : 200 mg/mL (ultrasonic)
Smiles
OC1(C(C2=CC=C(OC)C=C2)CN(C)C)CCCCC1
Molecular Formula
C17H27NO2
Molecular Weight
277.41
Precautions
H302, H315, H319, H335
References & Citations
[1]Bymaster FP, et al. Comparative affinity of duloxetine and venlafaxine for serotonin and norepinephrine transporters in vitro and in vivo, human serotonin receptor subtypes, and other neuronal receptors. Neuropsychopharmacology. 2001 Dec;25 (6) :871-80.|[2]Goeringer KE, et al. Postmortem tissue concentrations of venlafaxine. Forensic Sci Int. 2001 Sep 15;121 (1-2) :70-5.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched
Citation 01
Int Immunopharmacol. 2025 Jan 6:147:113969.|J Med Chem. 2025 May 8;68 (9) :9176-9201.|Neurosci Bull. 2025 Jul;41 (7) :1229-1245.|J Agric Food Chem. 2021 Nov 17;69 (45) :13618-13627.|Water Res. 2025 Oct 1;288 (Pt B) :124709.
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