PIM-1/CK2-IN-2

PIM-1/CK2-IN-2 (compound 3aA) is a PIM-1/CK2 inhibitor. PIM-1/CK2-IN-2 can induce the mitochondrial apoptotic pathway in CCRF-CEM cells. PIM-1/CK2-IN-2 can be used in cancer research[1].

Product Specifications

UNSPSC

12352101

Target

Apoptosis; Casein Kinase; Pim

Type

Reference compound

Related Pathways

Apoptosis; Cell Cycle/DNA Damage; JAK/STAT Signaling; Stem Cell/Wnt

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/pim-1-ck2-in-2.html

Smiles

O=C(C1=CC=CC=C1)CN2C=NC3=C(C(Br)=C(C(Br)=C32)Br)Br

Molecular Formula

C15H8Br4N2O

Molecular Weight

551.85

References & Citations

[1]Łukowska-Chojnacka, et al. "Synthesis and evaluation of anticancer activity of new 4, 5, 6, 7-tetrabromo-1H-benzimidazole derivatives." Bioorganic Chemistry (2024) : 107880.