PIM-1/CK2-IN-2
PIM-1/CK2-IN-2 (compound 3aA) is a PIM-1/CK2 inhibitor. PIM-1/CK2-IN-2 can induce the mitochondrial apoptotic pathway in CCRF-CEM cells. PIM-1/CK2-IN-2 can be used in cancer research[1].
Product Specifications
UNSPSC
12352101
Target
Apoptosis; Casein Kinase; Pim
Type
Reference compound
Related Pathways
Apoptosis; Cell Cycle/DNA Damage; JAK/STAT Signaling; Stem Cell/Wnt
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pim-1-ck2-in-2.html
Smiles
O=C(C1=CC=CC=C1)CN2C=NC3=C(C(Br)=C(C(Br)=C32)Br)Br
Molecular Formula
C15H8Br4N2O
Molecular Weight
551.85
References & Citations
[1]Łukowska-Chojnacka, et al. "Synthesis and evaluation of anticancer activity of new 4, 5, 6, 7-tetrabromo-1H-benzimidazole derivatives." Bioorganic Chemistry (2024) : 107880.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CK2; PIM1
Curated Selection
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