Anti-BRCA1-associated protein BRAP Monoclonal Antibody
Boster Bio Anti-BRCA1-associated protein BRAP Monoclonal Antibody catalog # M03573. Tested in ELISA, WB applications. This antibody reacts with Human.
Product Specifications
Synonyms
BRCA1-associated protein;2.3.2.27
Gene Name
BRAP
UniProt
Q7Z569
Host
Mouse
Reactivity
Human
Immunogen
Purified recombinant human BRAP protein fragments expressed in E.coli.
Clonality
Monoclonal
Clone
Clone: 1E7-C9-D10-B10
Tissue Specificity
Expressed in breast epithelial cell lines.
Applications
WB, ELISA
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Form
Liquid
Function
Negatively regulates MAP kinase activation by limiting the formation of Raf/MEK complexes probably by inactivation of the KSR1 scaffold protein. Also acts as a Ras responsive E3 ubiquitin ligase that, on activation of Ras, is modified by auto- polyubiquitination resulting in the release of inhibition of Raf/MEK complex formation. May also act as a cytoplasmic retention protein with a role in regulating nuclear transport.
Molecular Weight
67305 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Fragment
IgG
Other Gene Names
BRCA1-associated protein
Subcellular Location
Cytoplasm
Protein Name
BRCA1-associated protein
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