Anti-Collagen alpha-1 (XII) chain COL12A1 Antibody
Boster Bio Anti-Collagen alpha-1 (XII) chain COL12A1 Antibody catalog # A05008-1. Tested in ELISA, WB applications. This antibody reacts with Human.
Product Specifications
Synonyms
Collagen alpha-1 (XII) chain; COL12A1; COL12A1L;
Gene Name
COL12A1
UniProt
Q99715
Host
Rabbit
Reactivity
Human
Immunogen
Synthetic peptide from human COL12A1 protein.
Clonality
Polyclonal
Tissue Specificity
Found in collagen I-containing tissues: both isoform 1 and isoform 2 appear in amnion, chorion, skeletal muscle, small intestine, and in cell culture of dermal fibroblasts, keratinocytes and endothelial cells. Only isoform 2 is found in lung, placenta, kidney and a squamous cell carcinoma cell line. Isoform 1 is also present in the corneal epithelial Bowman's membrane (BM) and the interfibrillar matrix of the corneal stroma, but it is not detected in the limbal BM.
Applications
WB, ELISA
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Form
Liquid
Function
Type XII collagen interacts with type I collagen- containing fibrils, the COL1 domain could be associated with the surface of the fibrils, and the COL2 and NC3 domains may be localized in the perifibrillar matrix. .
Molecular Weight
333147 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Fragment
IgG
Other Gene Names
Collagen alpha-1 (XII) chain
Subcellular Location
Secreted, extracellular space, extracellular matrix .
Protein Name
Collagen alpha-1 (XII) chain
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