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Anti-CD108 SEMA7A Antibody

Boster Bio Anti-CD108 SEMA7A Antibody catalog # A03832-1. Tested in ELISA, IHC applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Semaphorin-7A; CDw108; JMH blood group antigen; John-Milton-Hargen human blood group Ag; Semaphorin-K1; Sema K1; Semaphorin-L; Sema L; CD108; SEMA7A; CD108, SEMAL;

Gene Name

SEMA7A

UniProt

O75326

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide from human protein at AA range: 101-150

Clonality

Polyclonal

Tissue Specificity

Detected in skin keratinocytes and on endothelial cells from skin blood vessels (at protein level) . Expressed in fibroblasts, keratinocytes, melanocytes, placenta, testis, ovary, spleen, brain, spinal chord, lung, heart, adrenal gland, lymph nodes, thymus, intestine and kidney.

Applications

IHC, ELISA

Purification

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Concentration

1 mg/ml

Form

Liquid

Function

Plays an important role in integrin-mediated signaling and functions both in regulating cell migration and immune responses. Promotes formation of focal adhesion complexes, activation of the protein kinase PTK2/FAK1 and subsequent phosphorylation of MAPK1 and MAPK3. Promotes production of proinflammatory cytokines by monocytes and macrophages. Plays an important role in modulating inflammation and T-cell-mediated immune responses. Promotes axon growth in the embryonic olfactory bulb. Promotes attachment, spreading and dendrite outgrowth in melanocytes.

Molecular Weight

74824 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A03832-1

Product MSDS

https://www.bosterbio.com/msds?sku=A03832-1

Fragment

IgG

Other Gene Names

Semaphorin-7A

Subcellular Location

Cell membrane

Protein Name

Semaphorin-7A

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