Anti-Wnt-1 Monoclonal Antibody
Boster Bio Anti-Wnt-1 Monoclonal Antibody catalog # M00354. Tested in ELISA, Flow Cytometry, IF, IHC, WB applications. This antibody reacts with Human, Mouse.
Product Specifications
Synonyms
Proto-oncogene Wnt-1; Proto-oncogene Int-1 homolog; WNT1; INT1;
Gene Name
WNT1
UniProt
P04628
Host
Mouse
Reactivity
Human, Mouse
Immunogen
Purified recombinant fragment of Wnt-1 expressed in E. Coli.
Clonality
Monoclonal
Clone
Clone: 10C8
Applications
WB, IHC, IF, Flow Cytometry, ELISA
Purification
Affinity purification
Concentration
1 mg/ml
Form
Liquid
Function
Ligand for members of the frizzled family of seven transmembrane receptors (Probable) . Acts in the canonical Wnt signaling pathway by promoting beta-catenin-dependent transcriptional activation (PubMed:23499309, PubMed:26902720, PubMed:28528193, PubMed:23656646) . In some developmental processes, is also a ligand for the coreceptor RYK, thus triggering Wnt signaling (By similarity) . Plays an essential role in the development of the embryonic brain and central nervous system (CNS) (By similarity) . Has a role in osteoblast function, bone development and bone homeostasis (PubMed:23499309, PubMed:23656646) .
Molecular Weight
40982 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Fragment
IgG
Other Gene Names
Proto-oncogene Wnt-1
Subcellular Location
Secreted, extracellular space, extracellular matrix . Secreted
Protein Name
Proto-oncogene Wnt-1
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