Anti-TAB2 Monoclonal Antibody
Boster Bio Anti-TAB2 Monoclonal Antibody catalog # M02499. Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human.
Product Specifications
Synonyms
TGF-beta-activated kinase 1 and MAP3K7-binding protein 2; Mitogen-activated protein kinase kinase kinase 7-interacting protein 2; TAK1-binding protein 2; TAB-2; TGF-beta-activated kinase 1-binding protein 2; TAB2; KIAA0733, MAP3K7IP2;
Gene Name
TAB2
UniProt
Q9NYJ8
Host
Mouse
Reactivity
Human
Immunogen
Purified recombinant fragment of human TAB2 expressed in E. Coli.
Clonality
Monoclonal
Clone
Clone: 3B5
Tissue Specificity
Widely expressed. In the embryo, expressed in the ventricular trabeculae, endothelial cells of the conotruncal cushions of the outflow tract and in the endothelial cells lining the developing aortic valves.
Applications
WB, Flow Cytometry, ELISA
Purification
Affinity purification
Concentration
1 mg/ml
Form
Liquid
Function
Adapter linking MAP3K7/TAK1 and TRAF6. Promotes MAP3K7 activation in the IL1 signaling pathway. The binding of 'Lys-63'- linked polyubiquitin chains to TAB2 promotes autophosphorylation of MAP3K7 at 'Thr-187'. Involved in heart development.
Molecular Weight
76494 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Fragment
IgG
Other Gene Names
TGF-beta-activated kinase 1 and MAP3K7-binding protein 2
Subcellular Location
Membrane
Protein Name
TGF-beta-activated kinase 1 and MAP3K7-binding protein 2
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