Anti-Polycomb protein SUZ12 SUZ12 Monoclonal Antibody
Boster Bio Anti-Polycomb protein SUZ12 SUZ12 Monoclonal Antibody catalog # M00583-1. Tested in ELISA, IHC, WB applications. This antibody reacts with Human.
Product Specifications
Synonyms
Polycomb protein SUZ12; Chromatin precipitated E2F target 9 protein; ChET 9 protein; Joined to JAZF1 protein; Suppressor of zeste 12 protein homolog; SUZ12; CHET9, JJAZ1, KIAA0160;
Gene Name
SUZ12
UniProt
Q15022
Host
Mouse
Reactivity
Human
Immunogen
Purified recombinant fragment of human SUZ12 expressed in E. Coli.
Clonality
Monoclonal
Clone
Clone: 3D10
Tissue Specificity
Overexpressed in breast and colon cancer.
Applications
WB, IHC, ELISA
Purification
Affinity purification
Concentration
1 mg/ml
Form
Liquid
Function
Polycomb group (PcG) protein. Component of the PRC2/EED- EZH2 complex, which methylates 'Lys-9' (H3K9me) and 'Lys-27' (H3K27me) of histone H3, leading to transcriptional repression of the affected target gene. The PRC2/EED-EZH2 complex may also serve as a recruiting platform for DNA methyltransferases, thereby linking two epigenetic repression systems. Genes repressed by the PRC2/EED-EZH2 complex include HOXC8, HOXA9, MYT1 and CDKN2A.
Molecular Weight
83055 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Fragment
IgG
Other Gene Names
Polycomb protein SUZ12
Subcellular Location
Nucleus
Protein Name
Polycomb protein SUZ12
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