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Anti-PARL Monoclonal Antibody

Boster Bio Anti-PARL Monoclonal Antibody catalog # M08686. Tested in ELISA, WB applications. This antibody reacts with Human.

Product Specifications

Synonyms

Presenilins-associated rhomboid-like protein, mitochondrial;3.4.21.105; Mitochondrial intramembrane cleaving protease PARL; P-beta; Pbeta; PARL; PSARL; PRO2207;

Gene Name

PARL

UniProt

Q9H300

Host

Mouse

Reactivity

Human

Immunogen

Purified recombinant fragment of PARL (aa112-167) expressed in E. Coli.

Clonality

Monoclonal

Clone

Clone: 8C4B2 / 1H12E10

Applications

WB, ELISA

Purification

Affinity purification

Concentration

1 mg/ml

Form

Liquid

Function

Required for the control of apoptosis during postnatal growth. Essential for proteolytic processing of an antiapoptotic form of OPA1 which prevents the release of mitochondrial cytochrome c in response to intrinsic apoptoptic signals (By similarity) . Promotes changes in mitochondria morphology regulated by phosphorylation of P-beta domain.

Molecular Weight

42190 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Fragment

IgG

Other Gene Names

Presenilins-associated rhomboid-like protein, mitochondrial

Subcellular Location

Mitochondrion inner membrane

Protein Name

Presenilins-associated rhomboid-like protein, mitochondrial

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