Anti-Nkx-2.5 Monoclonal Antibody
Boster Bio Anti-Nkx-2.5 Monoclonal Antibody catalog # M00738. Tested in ELISA, WB applications. This antibody reacts with Human.
Product Specifications
Synonyms
Homeobox protein Nkx-2.5; Cardiac-specific homeobox; Homeobox protein CSX; Homeobox protein NK-2 homolog E; NKX2-5; CSX, NKX2.5, NKX2E;
Gene Name
NKX2-5
UniProt
P52952
Host
Mouse
Reactivity
Human
Immunogen
Purified recombinant fragment of human Nkx-2.5 expressed in E. Coli.
Clonality
Monoclonal
Clone
Clone: 20
Tissue Specificity
Expressed only in the heart.
Applications
WB, ELISA
Purification
Affinity purification
Concentration
1 mg/ml
Form
Liquid
Function
Implicated in commitment to and/or differentiation of the myocardial lineage. Acts as a transcriptional activator of ANF in cooperation with GATA4 (By similarity) . Binds to the core DNA motif of NPPA promoter (PubMed:22849347, PubMed:26926761) . It is transcriptionally controlled by PBX1 and acts as a transcriptional repressor of CDKN2B (By similarity) . It is required for spleen development.
Molecular Weight
34918 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Fragment
IgG
Other Gene Names
Homeobox protein Nkx-2.5
Subcellular Location
Nucleus .
Protein Name
Homeobox protein Nkx-2.5
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