Anti-MDMX MDM4 Monoclonal Antibody
Boster Bio Anti-MDMX MDM4 Monoclonal Antibody catalog # M01889. Tested in ELISA, IF, IHC, WB applications. This antibody reacts with Human.
Product Specifications
Synonyms
Protein Mdm4; Double minute 4 protein; Mdm2-like p53-binding protein; Protein Mdmx; p53-binding protein Mdm4; MDM4; MDMX;
Gene Name
MDM4
UniProt
O15151
Host
Mouse
Reactivity
Human
Immunogen
Purified recombinant fragment of human MDMX expressed in E. Coli.
Clonality
Monoclonal
Clone
Clone: 2D10F4
Tissue Specificity
Expressed in all tissues tested with high levels in thymus.
Applications
WB, IHC, IF, ELISA
Purification
Affinity purification
Concentration
1 mg/ml
Form
Liquid
Function
Inhibits p53/TP53- and TP73/p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Inhibits degradation of MDM2. Can reverse MDM2-targeted degradation of TP53 while maintaining suppression of TP53 transactivation and apoptotic functions.
Molecular Weight
54864 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Fragment
IgG
Other Gene Names
Protein Mdm4
Subcellular Location
Nucleus.
Protein Name
Protein Mdm4
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