Anti-Crk II Monoclonal Antibody
Boster Bio Anti-Crk II Monoclonal Antibody catalog # M02533-1. Tested in ELISA, Flow Cytometry, IF, IHC, WB applications. This antibody reacts with Human.
Product Specifications
Synonyms
Adapter molecule crk; Proto-oncogene c-Crk; p38; CRK;
Gene Name
CRK
UniProt
P46108
Host
Mouse
Reactivity
Human
Immunogen
Purified recombinant fragment of human Crk II expressed in E. Coli.
Clonality
Monoclonal
Clone
Clone: 3G11C1
Applications
WB, IHC, IF, Flow Cytometry, ELISA
Purification
Affinity purification
Concentration
1 mg/ml
Form
Liquid
Function
Isoform Crk-II: Regulates cell adhesion, spreading and migration. Mediates attachment-induced MAPK8 activation, membrane ruffling and cell motility in a Rac-dependent manner. Involved in phagocytosis of apoptotic cells and cell motility via its interaction with DOCK1 and DOCK4. May regulate the EFNA5-EPHA3 signaling.
Molecular Weight
33831 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Fragment
IgG
Other Gene Names
Adapter molecule crk
Subcellular Location
Cytoplasm . Cell membrane . Translocated to the plasma membrane upon cell adhesion. .
Protein Name
Adapter molecule crk
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