Anti-BMPR-II BMPR2 Monoclonal Antibody
Boster Bio Anti-BMPR-II BMPR2 Monoclonal Antibody catalog # M00324. Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Monkey, Mouse, Rat.
Product Specifications
Synonyms
Bone morphogenetic protein receptor type-2; BMP type-2 receptor; BMPR-2;2.7.11.30; Bone morphogenetic protein receptor type II; BMP type II receptor; BMPR-II; BMPR2; PPH1;
Gene Name
BMPR2
UniProt
Q13873
Host
Mouse
Reactivity
Human, Mouse, Rat, Monkey
Immunogen
Purified recombinant fragment of human BMPR-II expressed in E. Coli.
Clonality
Monoclonal
Clone
Clone: 1F12
Tissue Specificity
Highly expressed in heart and liver.
Applications
WB, IHC, ELISA
Purification
Affinity purification
Concentration
1 mg/ml
Form
Liquid
Function
On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Binds to BMP7, BMP2 and, less efficiently, BMP4. Binding is weak but enhanced by the presence of type I receptors for BMPs. Mediates induction of adipogenesis by GDF6.
Molecular Weight
115201 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Fragment
IgG
Other Gene Names
Bone morphogenetic protein receptor type-2
Subcellular Location
Cell membrane
Protein Name
Bone morphogenetic protein receptor type-2
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