Anti-BMPR-II BMPR2 Monoclonal Antibody

Boster Bio Anti-BMPR-II BMPR2 Monoclonal Antibody catalog # M00324. Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Monkey, Mouse, Rat.

Product Specifications

Synonyms

Bone morphogenetic protein receptor type-2; BMP type-2 receptor; BMPR-2;2.7.11.30; Bone morphogenetic protein receptor type II; BMP type II receptor; BMPR-II; BMPR2; PPH1;

Gene Name

BMPR2

UniProt

Q13873

Host

Mouse

Reactivity

Human, Mouse, Rat, Monkey

Immunogen

Purified recombinant fragment of human BMPR-II expressed in E. Coli.

Clonality

Monoclonal

Clone

Clone: 1F12

Tissue Specificity

Highly expressed in heart and liver.

Applications

WB, IHC, ELISA

Purification

Affinity purification

Concentration

1 mg/ml

Form

Liquid

Function

On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Binds to BMP7, BMP2 and, less efficiently, BMP4. Binding is weak but enhanced by the presence of type I receptors for BMPs. Mediates induction of adipogenesis by GDF6.