Anti-AAT SERPINA1 Monoclonal Antibody
Boster Bio Anti-AAT SERPINA1 Monoclonal Antibody catalog # M00720-2. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse.
Product Specifications
Synonyms
Alpha-1-antitrypsin; Alpha-1 protease inhibitor; Alpha-1-antiproteinase; Serpin A1; Short peptide from AAT; SPAAT; SERPINA1; AAT, PI; PRO0684, PRO2209;
Gene Name
SERPINA1
UniProt
P01009
Host
Mouse
Reactivity
Human, Mouse
Immunogen
Purified recombinant fragment of human AAT expressed in E. Coli.
Clonality
Monoclonal
Clone
Clone: 2B12
Tissue Specificity
Ubiquitous. Expressed in leukocytes and plasma.
Applications
WB, ELISA
Purification
Affinity purification
Concentration
1 mg/ml
Form
Liquid
Function
Inhibitor of serine proteases. Its primary target is elastase, but it also has a moderate affinity for plasmin and thrombin. Irreversibly inhibits trypsin, chymotrypsin and plasminogen activator. The aberrant form inhibits insulin-induced NO synthesis in platelets, decreases coagulation time and has proteolytic activity against insulin and plasmin.
Molecular Weight
46737 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Fragment
IgG
Other Gene Names
Alpha-1-antitrypsin
Subcellular Location
Secreted. Endoplasmic reticulum. The S and Z allele are not secreted effectively and accumulate intracellularly in the endoplasmic reticulum.
Protein Name
Alpha-1-antitrypsin
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