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Anti-kappa beta NFKBIB Monoclonal Antibody

Boster Bio Anti-kappa beta NFKBIB Monoclonal Antibody catalog # M05766-2. Tested in IHC applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

NF-kappa-B inhibitor beta; NF-kappa-BIB; I-kappa-B-beta; IkB-B; IkB-beta; IkappaBbeta; Thyroid receptor-interacting protein 9; TR-interacting protein 9; TRIP-9; NFKBIB; IKBB, TRIP9;

Gene Name

NFKBIB

UniProt

Q15653

Host

Mouse

Reactivity

Human, Rat, Mouse

Immunogen

Recombinant Protein

Clonality

Monoclonal

Clone

Clone: 1F3

Tissue Specificity

Expressed in all tissues examined.

Applications

IHC

Purification

The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.

Concentration

1 mg/ml

Dilution

IHC 1:100-200

Form

Liquid

Function

Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. However, the unphosphorylated form resynthesized after cell stimulation is able to bind NF-kappa-B allowing its transport to the nucleus and protecting it to further NFKBIA- dependent inactivation. Association with inhibitor kappa B- interacting NKIRAS1 and NKIRAS2 prevent its phosphorylation rendering it more resistant to degradation, explaining its slower degradation.

Molecular Weight

37771 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Fragment

IgG

Other Gene Names

NF-kappa-B inhibitor beta

Subcellular Location

Cytoplasm . Nucleus .

Protein Name

NF-kappa-B inhibitor beta

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