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Anti-Neuregulin-3 NRG3 Antibody

Boster Bio Anti-Neuregulin-3 NRG3 Antibody catalog # A06681. Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Mouse.

Product Specifications

Synonyms

Pro-neuregulin-3, membrane-bound isoform; Pro-NRG3; Neuregulin-3; NRG-3; NRG3;

Gene Name

NRG3

UniProt

P56975

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from the Internal region of human NRG3. AA range:311-360

Clonality

Polyclonal

Tissue Specificity

Highly expressed in most regions of the brain with the exception of corpus callosum. Expressed at lower level in testis. Not detected in heart, placenta, lung, liver, skeletal muscle, kidney, pancreas, spleen, thymus, prostate, ovary, small intestine, colon and peripheral blood leukocytes.

Applications

WB, IHC, ELISA

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Form

Liquid

Function

Direct ligand for the ERBB4 tyrosine kinase receptor. Binding results in ligand-stimulated tyrosine phosphorylation and activation of the receptor. Does not bind to the EGF receptor, ERBB2 or ERBB3 receptors. May be a survival factor for oligodendrocytes.

Molecular Weight

77901 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Fragment

IgG

Other Gene Names

Pro-neuregulin-3, membrane-bound isoform

Subcellular Location

Pro-neuregulin-3, membrane-bound isoform: Cell membrane ; Single-pass type I membrane protein . Does not seem to be active. .

Protein Name

Pro-neuregulin-3, membrane-bound isoform

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