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Anti-Caspase 9 CASP9 Monoclonal Antibody

Boster Bio Anti-Caspase 9 CASP9 Monoclonal Antibody catalog # M00080-5. Tested in IP, IF, IHC, WB applications. This antibody reacts with Chicken, Human, Mouse, Rat.

Product Specifications

Synonyms

Caspase-9; CASP-9;3.4.22.62

Gene Name

CASP9

UniProt

P55211

Host

Mouse

Reactivity

Human, Mouse, Rat, Chicken

Immunogen

Synthetic Peptide of Caspase 9

Clonality

Monoclonal

Clone

Clone: 43891

Tissue Specificity

Ubiquitous, with highest expression in the heart, moderate expression in liver, skeletal muscle, and pancreas. Low levels in all other tissues. Within the heart, specifically expressed in myocytes.

Applications

IP, IF, IHC, WB

Purification

The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.

Concentration

1 mg/ml

Form

Liquid

Function

Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf- 1 leads to activation of the protease which then cleaves and activates caspase-3. Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly (ADP- ribose) polymerase (PARP) .

Molecular Weight

46281 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=M00080-5

Product MSDS

https://www.bosterbio.com/msds?sku=M00080-5

Fragment

IgG1

Other Gene Names

Caspase-9

Protein Name

Caspase-9

Curated Selection

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