Anti-Caspase 9 CASP9 Monoclonal Antibody
Boster Bio Anti-Caspase 9 CASP9 Monoclonal Antibody catalog # M00080-5. Tested in IP, IF, IHC, WB applications. This antibody reacts with Chicken, Human, Mouse, Rat.
Product Specifications
Synonyms
Caspase-9; CASP-9;3.4.22.62
Gene Name
CASP9
UniProt
P55211
Host
Mouse
Reactivity
Human, Mouse, Rat, Chicken
Immunogen
Synthetic Peptide of Caspase 9
Clonality
Monoclonal
Clone
Clone: 43891
Tissue Specificity
Ubiquitous, with highest expression in the heart, moderate expression in liver, skeletal muscle, and pancreas. Low levels in all other tissues. Within the heart, specifically expressed in myocytes.
Applications
IP, IF, IHC, WB
Purification
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Concentration
1 mg/ml
Form
Liquid
Function
Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf- 1 leads to activation of the protease which then cleaves and activates caspase-3. Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly (ADP- ribose) polymerase (PARP) .
Molecular Weight
46281 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Fragment
IgG1
Other Gene Names
Caspase-9
Protein Name
Caspase-9
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