Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Anti-ABCB5 Monoclonal Antibody

Boster Bio Anti-ABCB5 Monoclonal Antibody catalog # M02979. Tested in WB applications. This antibody reacts with Human.

Product Specifications

Synonyms

ATP-binding cassette sub-family B member 5; ABCB5 P-gp; P-glycoprotein ABCB5; ABCB5;

Gene Name

ABCB5

UniProt

Q2M3G0

Host

Mouse

Reactivity

Human

Immunogen

Synthetic Peptide of ABCB5

Clonality

Monoclonal

Clone

Clone: 11A2

Tissue Specificity

Expressed by CD133-expressing progenitor cells among epidermal melanocytes (at protein level) . Widely expressed with specific expression in pigment cells. Highly expressed in several malignant tissues: highly expressed in clinical melanomas, with low expression in normal skin. In melanoma, marks malignant melanoma-initiating cells (MMIC), in which clinical virulence resides as a consequence of unlimited self-renewal capacity, resulting in inexorable tumor progression and metastasis. Also highly expressed in a number of leukemia cells. Expressed in basal limbal epithelium.

Applications

WB

Purification

The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.

Concentration

1 mg/ml

Dilution

WB 1:2000

Form

Liquid

Function

Drug efflux transporter present in a number of stem cells that acts as a regulator of cellular differentiation. Able to mediate efflux from cells of the rhodamine dye and of the therapeutic drug doxorubicin. Specifically present in limbal stem cells, where it plays a key role in corneal development and repair.

Molecular Weight

138641 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=M02979

Product MSDS

https://www.bosterbio.com/msds?sku=M02979

Fragment

IgG

Other Gene Names

ATP-binding cassette sub-family B member 5

Subcellular Location

Cell membrane

Protein Name

ATP-binding cassette sub-family B member 5

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

Human ANKRD53 shRNA Plasmid
abx962713-01 150 µg

Human ANKRD53 shRNA Plasmid

Ask
View Details
Human ANKRD53 shRNA Plasmid
abx962713-02 300 µg

Human ANKRD53 shRNA Plasmid

Ask
View Details
Delta 4 Recombinant Protein His Tag Lyophilized 100UG
IDL4RHISLY100UG 100 µg

Delta 4 Recombinant Protein His Tag Lyophilized 100UG

Ask
View Details
RELA (Phospho-Ser536) Rabbit pAb
E2615329 100ul

RELA (Phospho-Ser536) Rabbit pAb

Ask
View Details
Rabbit anti-Drosophila mauritiana (Fruit fly) Amy-d Polyclonal Antibody
MBS7160560 Inquire

Rabbit anti-Drosophila mauritiana (Fruit fly) Amy-d Polyclonal Antibody

Ask
View Details
Human Calcium-activated chloride channel regulator 4, CLCA4 ELISA Kit
MBS1607329-01 48 Well

Human Calcium-activated chloride channel regulator 4, CLCA4 ELISA Kit

Ask
View Details