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Anti-IL-1RII IL1R2 Antibody

Boster Bio Anti-IL-1RII IL1R2 Antibody catalog # A03106-3. Tested in ELISA, IHC-P, WB applications. This antibody reacts with Human.

Product Specifications

Synonyms

Interleukin-1 receptor type 2; IL-1R-2; IL-1RT-2; IL-1RT2; CD121 antigen-like family member B; CDw121b; IL-1 type II receptor; Interleukin-1 receptor beta; IL-1R-beta; Interleukin-1 receptor type II; CD121b; Interleukin-1 receptor type 2, membrane form; mIL-1R2; mIL-1RII; Interleukin-1 receptor type 2, soluble form; sIL-1R2; sIL-1RII; IL1R2; IL1RB;

Gene Name

IL1R2

UniProt

P27930

Host

Rabbit

Reactivity

Human

Immunogen

The antiserum was produced against synthesized peptide derived from the Internal region of human IL1R2. AA range:141-190

Clonality

Polyclonal

Applications

ELISA, IHC-P, WB

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Form

Liquid

Function

Non-signaling receptor for IL1A, IL1B and IL1RN. Reduces IL1B activities. Serves as a decoy receptor by competetive binding to IL1B and preventing its binding to IL1R1. Also modulates cellular response through non-signaling association with IL1RAP after binding to IL1B. IL1R2 (membrane and secreted forms) preferentially binds IL1B and poorly IL1A and IL1RN. The secreted IL1R2 recruits secreted IL1RAP with high affinity; this complex formation may be the dominant mechanism for neutralization of IL1B by secreted/soluble receptors.

Molecular Weight

45421 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Fragment

IgG

Other Gene Names

Interleukin-1 receptor type 2

Subcellular Location

Isoform Short: Secreted

Protein Name

Interleukin-1 receptor type 2

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