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Anti-HSP40-4 DNAJA1 Antibody

Boster Bio Anti-HSP40-4 DNAJA1 Antibody catalog # A04151. Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

DnaJ homolog subfamily A member 1; DnaJ protein homolog 2; HSDJ; Heat shock 40 kDa protein 4; Heat shock protein J2; HSJ-2; Human DnaJ protein 2; hDj-2; DNAJA1; DNAJ2, HDJ2, HSJ2, HSPF4;

Gene Name

DNAJA1

UniProt

P31689

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from human HSP40-4.

Clonality

Polyclonal

Tissue Specificity

Ubiquitous. Isoform 2 is highly expressed in testis and lung, but detected at low levels in thymus, prostate, colon and liver.

Applications

WB, IHC, ELISA

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Form

Liquid

Function

Co-chaperone for HSPA8/Hsc70 (PubMed:10816573) . Stimulates ATP hydrolysis, but not the folding of unfolded proteins mediated by HSPA1A (in vitro) (PubMed:24318877) . Plays a role in protein transport into mitochondria via its role as co- chaperone. Functions as co-chaperone for HSPA1B and negatively regulates the translocation of BAX from the cytosol to mitochondria in response to cellular stress, thereby protecting cells against apoptosis (PubMed:14752510) . Promotes apoptosis in response to cellular stress mediated by exposure to anisomycin or UV (PubMed:24512202) .

Molecular Weight

44868 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A04151

Product MSDS

https://www.bosterbio.com/msds?sku=A04151

Fragment

IgG

Other Gene Names

DnaJ homolog subfamily A member 1

Subcellular Location

Membrane

Protein Name

DnaJ homolog subfamily A member 1

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