What is the catalog number for Anti-THC2 MASTL Antibody?

The catalog number for Anti-THC2 MASTL Antibody is A04567-2.

Is Anti-THC2 MASTL Antibody in stock?

Anti-THC2 MASTL Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-THC2 MASTL Antibody?

The safety data sheet for Anti-THC2 MASTL Antibody is available here: https://www.bosterbio.com/msds?sku=A04567-2.

Anti-THC2 MASTL Antibody

Boster Bio Anti-THC2 MASTL Antibody catalog # A04567-2. Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Mouse.

Product Specifications

Synonyms

Serine/threonine-protein kinase greatwall; GW; GWL; hGWL;2.7.11.1; Microtubule-associated serine/threonine-protein kinase-like; MAST-L; MASTL; GW, GWL, THC2;

Gene Name

MASTL

UniProt

Q96GX5

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from human MASTL. AA range:821-870

Clonality

Polyclonal

Applications

WB, IHC, ELISA

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Form

Liquid

Function

Serine/threonine kinase that plays a key role in M phase by acting as a regulator of mitosis entry and maintenance. Acts by promoting the inactivation of protein phosphatase 2A (PP2A) during M phase: does not directly inhibit PP2A but acts by mediating phosphorylation and subsequent activation of ARPP19 and ENSA at 'Ser-62' and 'Ser-67', respectively. ARPP19 and ENSA are phosphatase inhibitors that specifically inhibit the PPP2R2D (PR55-delta) subunit of PP2A. Inactivation of PP2A during M phase is essential to keep cyclin-B1-CDK1 activity high. Following DNA damage, it is also involved in checkpoint recovery by being inhibited. Phosphorylates histone protein in vitro; however such activity is unsure in vivo. May be involved in megakaryocyte differentiation.