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Anti-Synuclein-beta SNCB Antibody

Boster Bio Anti-Synuclein-beta SNCB Antibody catalog # A07381-1. Tested in ELISA, IF, IHC, WB applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Beta-synuclein; SNCB;

Gene Name

SNCB

UniProt

Q16143

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

The antiserum was produced against synthesized peptide derived from human Synuclein beta. AA range:85-134

Clonality

Polyclonal

Tissue Specificity

Expressed predominantly in brain; concentrated in presynaptic nerve terminals.

Applications

WB, IHC, IF, ELISA

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Form

Liquid

Function

Non-amyloid component of senile plaques found in Alzheimer disease. Could act as a regulator of SNCA aggregation process. Protects neurons from staurosporine and 6-hydroxy dopamine (6OHDA) -stimulated caspase activation in a p53/TP53- dependent manner. Contributes to restore the SNCA anti-apoptotic function abolished by 6OHDA. Not found in the Lewy bodies associated with Parkinson disease.

Molecular Weight

14288 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Fragment

IgG

Other Gene Names

Beta-synuclein

Subcellular Location

Cytoplasm.

Protein Name

Beta-synuclein

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