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Anti-SMRTe NCOR2 Antibody

Boster Bio Anti-SMRTe NCOR2 Antibody catalog # A01412-1. Tested in ELISA, IF, IHC applications. This antibody reacts with Human.

Product Specifications

Synonyms

Nuclear receptor corepressor 2 ; N-CoR2 ; CTG repeat protein 26; SMAP270; Silencing mediator of retinoic acid and thyroid hormone receptor ; SMRT ; T3 receptor-associating factor; TRAC; Thyroid-, retinoic-acid-receptor-associated corepressor; NCOR2

Gene Name

NCOR2

UniProt

Q9Y618

Host

Rabbit

Reactivity

Human

Immunogen

The antiserum was produced against synthesized peptide derived from human NCOR2. AA range:511-560

Clonality

Polyclonal

Tissue Specificity

Ubiquitous. High levels of expression are detected in lung, spleen and brain.

Applications

IHC, IF, ELISA

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Form

Liquid

Function

Transcriptional corepressor (PubMed:20812024) . Mediates the transcriptional repression activity of some nuclear receptors by promoting chromatin condensation, thus preventing access of the basal transcription. Isoform 1 and isoform 4 have different affinities for different nuclear receptors. Involved in the regulation BCL6-dependent of the germinal center (GC) reactions, mainly through the control of the GC B-cells proliferation and survival. Recruited by ZBTB7A to the androgen response elements/ARE on target genes, negatively regulates androgen receptor signaling and androgen-induced cell proliferation (PubMed:20812024) .

Molecular Weight

273657 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Fragment

IgG

Other Gene Names

Nuclear receptor corepressor 2

Subcellular Location

Nucleus.

Protein Name

Nuclear receptor corepressor 2

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