NRP1 antagonist 1
NRP1 antagonist 1 (compound 12a) is a potent NRP1 antagonist with an IC50 of 19.1 μM. NRP1 antagonist 1 has the potential for cancer research[1].
Product Specifications
CAS Number
[2569598-01-0]
UNSPSC
12352005
Target
Complement System
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/nrp1-antagonist-1.html
Purity
99.71
Solubility
DMSO : 83.33 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(NC1=NN=C(CC)S1)CSC2=NN=C(C3=CC=C(C)C=C3)N2C4=CC=CC(C)=C4
Molecular Formula
C22H22N6OS2
Molecular Weight
450.58
References & Citations
[1]Kewen Peng, et al. Discovery of novel nonpeptide small-molecule NRP1 antagonists: Virtual screening, molecular simulation and structural modification. Bioorg Med Chem. 2020 Jan 1;28 (1) :115183.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
47193114 3x 1.0 µg
Tnfaip8 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Mouse)
Sign In for Pricing
View Details K6396604 1.0 µg DNA
RGD1309104 sgRNA CRISPR Lentivector (Rat) (Target 3)
Sign In for Pricing
View Details NBP2-27339AF647 0.1 mL
Mouse Monoclonal IL-22 Antibody (8F11E2) [Alexa Fluor 647]
Sign In for Pricing
View Details