NRP1 antagonist 1

NRP1 antagonist 1 (compound 12a) is a potent NRP1 antagonist with an IC50 of 19.1 μM. NRP1 antagonist 1 has the potential for cancer research[1].

Product Specifications

CAS Number

[2569598-01-0]

UNSPSC

12352005

Target

Complement System

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/nrp1-antagonist-1.html

Purity

99.71

Solubility

DMSO : 83.33 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C(NC1=NN=C(CC)S1)CSC2=NN=C(C3=CC=C(C)C=C3)N2C4=CC=CC(C)=C4

Molecular Formula

C22H22N6OS2

Molecular Weight

450.58

References & Citations

[1]Kewen Peng, et al. Discovery of novel nonpeptide small-molecule NRP1 antagonists: Virtual screening, molecular simulation and structural modification. Bioorg Med Chem. 2020 Jan 1;28 (1) :115183.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

More Discoveries

Explore Other Products

Browse additional items from our catalog

272482 100 µg

Anti SARS Spike Protein Mab

View Details

PV284265 500 ng

NACC2 Protein Vector (Rat) (pPM-C-His)

View Details

A12860-10 10 mg

THIQ 10mg

View Details

CF806950 100 µg

53BP1 (TP53BP1) Mouse Monoclonal Antibody [Clone ID: OTI6D9]

View Details

249347-ML550 100 µL

NLGN4Y (Neuroligin 4, Y-Linked, KIAA0951) (MaxLight 550)

View Details

ES6747-01 50 µL

POLR3B rabbit pAb

View Details