NRP1 antagonist 1
NRP1 antagonist 1 (compound 12a) is a potent NRP1 antagonist with an IC50 of 19.1 μM. NRP1 antagonist 1 has the potential for cancer research[1].
Product Specifications
CAS Number
[2569598-01-0]
UNSPSC
12352005
Target
Complement System
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/nrp1-antagonist-1.html
Purity
99.71
Solubility
DMSO : 83.33 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(NC1=NN=C(CC)S1)CSC2=NN=C(C3=CC=C(C)C=C3)N2C4=CC=CC(C)=C4
Molecular Formula
C22H22N6OS2
Molecular Weight
450.58
References & Citations
[1]Kewen Peng, et al. Discovery of novel nonpeptide small-molecule NRP1 antagonists: Virtual screening, molecular simulation and structural modification. Bioorg Med Chem. 2020 Jan 1;28 (1) :115183.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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