Anti-RGS1 Antibody

Boster Bio Anti-RGS1 Antibody catalog # A04483. Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Regulator of G-protein signaling 1; RGS1; B-cell activation protein BL34

Gene Name

RGS1

UniProt

Q08116

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

The antiserum was produced against synthesized peptide derived from human RGS1. AA range:118-167

Clonality

Polyclonal

Tissue Specificity

Detected in peripheral blood monocytes (PubMed:10480894) . Expression is relatively low in B-cells and chronic lymphocytic leukemia B-cells; however, in other types of malignant B-cell such as non-Hodgkin lymphoma and hairy cell leukemia, expression is constitutively high (PubMed:8473738) .

Applications

WB, IHC, ELISA

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Form

Liquid

Function

Regulates G protein-coupled receptor signaling cascades, including signaling downstream of the N-formylpeptide chemoattractant receptors and leukotriene receptors (PubMed:10480894) . Inhibits B cell chemotaxis toward CXCL12 (By similarity) . Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form (PubMed:10480894, PubMed:18434541) .