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Anti-PinX1 Antibody

Boster Bio Anti-PinX1 Antibody catalog # A03576-1. Tested in ELISA, IHC applications. This antibody reacts with Human.

Product Specifications

Synonyms

PIN2/TERF1-interacting telomerase inhibitor 1; Liver-related putative tumor suppressor; Pin2-interacting protein X1; Protein 67-11-3; TRF1-interacting protein 1; PINX1; LPTL, LPTS;

Gene Name

PINX1

UniProt

Q96BK5

Host

Rabbit

Reactivity

Human

Immunogen

The antiserum was produced against synthesized peptide derived from human PINX1. AA range:121-170

Clonality

Polyclonal

Tissue Specificity

Ubiquitous; expressed at low levels. Not detectable in a number of hepatocarcinoma cell lines.

Applications

IHC, ELISA

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Form

Liquid

Function

Microtubule-binding protein essential for faithful chromosome segregation. Mediates TRF1 and TERT accumulation in nucleolus and enhances TRF1 binding to telomeres. Inhibits telomerase activity. May inhibit cell proliferation and act as tumor suppressor.

Molecular Weight

37035 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Fragment

IgG

Other Gene Names

PIN2/TERF1-interacting telomerase inhibitor 1

Subcellular Location

Nucleus. Nucleus, nucleolus. Chromosome, telomere. Chromosome, centromere, kinetochore. Localizes in nucleoli, at telomere speckles and to the outer plate of kinetochores. Localization to the kinetochore is mediated by its central region and depends on NDC80 and CENPE.

Protein Name

PIN2/TERF1-interacting telomerase inhibitor 1

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