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Anti-PHLDA3 Antibody

Boster Bio Anti-PHLDA3 Antibody catalog # A09241. Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Pleckstrin homology-like domain family A member 3; TDAG51/Ipl homolog 1; PHLDA3; TIH1;

Gene Name

PHLDA3

UniProt

Q9Y5J5

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

The antiserum was produced against synthesized peptide derived from human PHLDA3. AA range:21-70

Clonality

Polyclonal

Tissue Specificity

Widely expressed with lowest expression in liver and spleen.

Applications

WB, IHC, ELISA

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Form

Liquid

Function

P53/TP53-regulated repressor of Akt/AKT1 signaling. Represses AKT1 by preventing AKT1-binding to membrane lipids, thereby inhibiting AKT1 translocation to the cellular membrane and activation. Contributes to p53/TP53-dependent apoptosis by repressing AKT1 activity. Its direct transcription regulation by p53/TP53 may explain how p53/TP53 can negatively regulate AKT1. May act as a tumor suppressor.

Molecular Weight

13891 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Fragment

IgG

Other Gene Names

Pleckstrin homology-like domain family A member 3

Subcellular Location

Cytoplasm

Protein Name

Pleckstrin homology-like domain family A member 3

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