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Anti-Peroxin 19 PEX19 Antibody

Boster Bio Anti-Peroxin 19 PEX19 Antibody catalog # A03186-1. Tested in ELISA, IHC, WB applications. This antibody reacts with Human.

Product Specifications

Synonyms

Peroxisomal biogenesis factor 19;33 kDa housekeeping protein; Peroxin-19; Peroxisomal farnesylated protein; PEX19; HK33, PXF; OK/SW-cl.22;

Gene Name

PEX19

UniProt

P40855

Host

Rabbit

Reactivity

Human

Immunogen

The antiserum was produced against synthesized peptide derived from human PEX19. AA range:219-268

Clonality

Polyclonal

Tissue Specificity

Ubiquitously expressed. Isoform 1 is strongly predominant in all tissues except in utero where isoform 2 is the main form.

Applications

WB, IHC, ELISA

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Form

Liquid

Function

Necessary for early peroxisomal biogenesis. Acts both as a cytosolic chaperone and as an import receptor for peroxisomal membrane proteins (PMPs) . Binds and stabilizes newly synthesized PMPs in the cytoplasm by interacting with their hydrophobic membrane-spanning domains, and targets them to the peroxisome membrane by binding to the integral membrane protein PEX3. Excludes CDKN2A from the nucleus and prevents its interaction with MDM2, which results in active degradation of TP53.

Molecular Weight

32807 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Fragment

IgG

Other Gene Names

Peroxisomal biogenesis factor 19

Subcellular Location

Cytoplasm

Protein Name

Peroxisomal biogenesis factor 19

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