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Anti-PARD3A Antibody

Boster Bio Anti-PARD3A Antibody catalog # A01897-1. Tested in ELISA, IF, IHC, WB applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Partitioning defective 3 homolog; PAR-3; PARD-3; Atypical PKC isotype-specific-interacting protein; ASIP; CTCL tumor antigen se2-5; PAR3-alpha; PARD3

Gene Name

PARD3

UniProt

Q8TEW0

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

The antiserum was produced against synthesized peptide derived from human PARD3. AA range:1141-1190

Clonality

Polyclonal

Tissue Specificity

Widely expressed.

Applications

ELISA, IF, IHC, WB

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Form

Liquid

Function

Adapter protein involved in asymmetrical cell division and cell polarization processes (PubMed:27925688, PubMed:10954424) . Seems to play a central role in the formation of epithelial tight junctions (PubMed:27925688) . Targets the phosphatase PTEN to cell junctions (By similarity) . Involved in Schwann cell peripheral myelination (By similarity) . Association with PARD6B may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly (By similarity) . The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins (PubMed:10934474) . Required for establishment of neuronal polarity and normal axon formation in cultured hippocampal neurons (PubMed:19812038, PubMed:27925688) .

Molecular Weight

151423 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A01897-1

Product MSDS

https://www.bosterbio.com/msds?sku=A01897-1

Fragment

IgG

Other Gene Names

Partitioning defective 3 homolog

Subcellular Location

Cytoplasm . Endomembrane system

Protein Name

Partitioning defective 3 homolog

Curated Selection

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