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Anti-NKp30 NCR3 Antibody

Boster Bio Anti-NKp30 NCR3 Antibody catalog # A03182. Tested in ELISA, WB applications. This antibody reacts with Human, Rat.

Product Specifications

Synonyms

Natural cytotoxicity triggering receptor 3; Activating natural killer receptor p30; Natural killer cell p30-related protein; NK-p30; NKp30; CD337; NCR3;1C7, LY117;

Gene Name

NCR3

UniProt

O14931

Host

Rabbit

Reactivity

Human, Rat

Immunogen

The antiserum was produced against synthesized peptide derived from human NCR3. AA range:104-153

Clonality

Polyclonal

Tissue Specificity

Selectively expressed by all resting and activated NK cells and weakly expressed in spleen.

Applications

WB, ELISA

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Form

Liquid

Function

Cell membrane receptor of natural killer/NK cells that is activated by binding of extracellular ligands including BAG6 and NCR3LG1. Stimulates NK cells cytotoxicity toward neighboring cells producing these ligands. It controls, for instance, NK cells cytotoxicity against tumor cells. Engagement of NCR3 by BAG6 also promotes myeloid dendritic cells (DC) maturation, both through killing DCs that did not acquire a mature phenotype, and inducing the release by NK cells of TNFA and IFNG which promote DC maturation.

Molecular Weight

21593 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Fragment

IgG

Other Gene Names

Natural cytotoxicity triggering receptor 3

Subcellular Location

Cell membrane

Protein Name

Natural cytotoxicity triggering receptor 3

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