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Anti-NFATC2-interacting protein NFATc2IP Antibody

Boster Bio Anti-NFATC2-interacting protein NFATc2IP Antibody catalog # A11329. Tested in ELISA, WB applications. This antibody reacts with Human.

Product Specifications

Synonyms

NFATC2-interacting protein;45 kDa NF-AT-interacting protein;45 kDa NFAT-interacting protein; Nuclear factor of activated T-cells, cytoplasmic 2-interacting protein; NFATC2IP; NIP45;

Gene Name

NFATC2IP

UniProt

Q8NCF5

Host

Rabbit

Reactivity

Human

Immunogen

The antiserum was produced against synthesized peptide derived from human NFATC2IP. AA range:151-200

Clonality

Polyclonal

Applications

WB, ELISA

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Form

Liquid

Function

In T-helper 2 (Th2) cells, regulates the magnitude of NFAT-driven transcription of a specific subset of cytokine genes, including IL3, IL4, IL5 and IL13, but not IL2. Recruits PRMT1 to the IL4 promoter; this leads to enhancement of histone H4 'Arg-3'- methylation and facilitates subsequent histone acetylation at the IL4 locus, thus promotes robust cytokine expression (By similarity) . Down-regulates formation of poly-SUMO chains by UBE2I/UBC9 (By similarity) . .

Molecular Weight

45817 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Fragment

IgG

Other Gene Names

NFATC2-interacting protein

Subcellular Location

Nucleus . Cytoplasm . TRAF1 is associated with a fraction of NFATC2IP in the cytoplasm and prevents its translocation to the nucleus. .

Protein Name

NFATC2-interacting protein

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