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Anti-NEDL2 HECW2 Antibody (Internal)

Boster Bio Anti-NEDL2 HECW2 Antibody (Internal) catalog # A08779. Tested in ELISA, WB applications. This antibody reacts with Human.

Product Specifications

Synonyms

E3 ubiquitin-protein ligase HECW2;2.3.2.26; HECT, C2 and WW domain-containing protein 2; HECT-type E3 ubiquitin transferase HECW2; NEDD4-like E3 ubiquitin-protein ligase 2; HECW2; KIAA1301, NEDL2;

Gene Name

HECW2

UniProt

Q9P2P5

Host

Rabbit

Reactivity

Human

Immunogen

The antiserum was produced against synthesized peptide derived from human HECW2. AA range:481-530

Clonality

Polyclonal

Tissue Specificity

Predominantly expressed in adult brain, lung and heart.

Applications

WB, ELISA

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Form

Liquid

Function

E3 ubiquitin-protein ligase that mediates ubiquitination of TP73. Acts to stabilize TP73 and enhance activation of transcription by TP73 (PubMed:12890487) . Involved in the regulation of mitotic metaphase/anaphase transition (PubMed:24163370) .

Molecular Weight

175769 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Fragment

IgG

Other Gene Names

E3 ubiquitin-protein ligase HECW2

Subcellular Location

Cytoplasm . Cytoplasm, cytoskeleton, spindle

Protein Name

E3 ubiquitin-protein ligase HECW2

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