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Anti-Myt 1 PKMYT1 Antibody

Selected Variant

A06247-1

Size: 100 µL

Boster Bio Anti-Myt 1 PKMYT1 Antibody catalog # A06247-1. Tested in ELISA, IHC, WB applications. This antibody reacts with Human.

Product Specifications

Synonyms

Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase;2.7.11.1; Myt1 kinase; PKMYT1; MYT1;

Gene Name

PKMYT1

UniProt

Q99640

Host

Rabbit

Reactivity

Human

Immunogen

The antiserum was produced against synthesized peptide derived from human PKMYT1. AA range:49-98

Clonality

Polyclonal

Applications

WB, IHC, ELISA

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Form

Liquid

Function

Acts as a negative regulator of entry into mitosis (G2 to M transition) by phosphorylation of the CDK1 kinase specifically when CDK1 is complexed to cyclins. Mediates phosphorylation of CDK1 predominantly on 'Thr-14'. Also involved in Golgi fragmentation. May be involved in phosphorylation of CDK1 on 'Tyr-15' to a lesser degree, however tyrosine kinase activity is unclear and may be indirect. May be a downstream target of Notch signaling pathway during eye development.

Molecular Weight

54521 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Fragment

IgG

Other Gene Names

Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase

Subcellular Location

Endoplasmic reticulum membrane

Protein Name

Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase

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