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Melengestrol acetate

Melengestrol acetate is a progesterone derivative, acts as an orally active corticosteroid hormone to promote endometrial proliferation, pregnancy maintenance, and delay of menstrual activity[1]. Melengestrol Acetate is used as a contraceptive agent for growth promoting effects and suppression of estrus in animals. Melengestrol acetate inhibits both the androgen-dependent and -independent prostatic tumors in vivo and can be used for cancer research[2].

Product Specifications

CAS Number

[2919-66-6]

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

Progesterone Receptor

Type

Reference compound

Related Pathways

Vitamin D Related/Nuclear Receptor

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Cancer; Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/melengestrol-acetate.html

Purity

99.76

Solubility

DMSO : 25 mg/mL (ultrasonic)

Smiles

CC([C@@]1(OC(C)=O)C(C[C@@]2([H])[C@]3([H])C=C(C)C4=CC(CC[C@]4(C)[C@@]3([H])CC[C@]12C)=O)=C)=O

Molecular Formula

C25H32O4

Molecular Weight

396.52

Precautions

H302, H315, H319, H335

References & Citations

[1]G M Padilla, et al. Melengestrol acetate and megestrol acetate are prostatic tumor inhibiting agents. Biochem Cell Biol. 1990 Oct;68 (10) :1181-8.|[2]G W DUNCAN, et al. BIOLOGIC EFFECTS OF MELENGESTROL ACETATE. Fertil Steril. Jul-Aug 1964;15:416-32.|[3]https://www.sciencedirect.com/topics/agricultural-and-biological-sciences/melengestrol-acetate

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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