Anti-MGMT Antibody
Boster Bio Anti-MGMT Antibody catalog # A01012-1. Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Rat.
Product Specifications
Synonyms
Methylated-DNA--protein-cysteine methyltransferase;2.1.1.63;6-O-methylguanine-DNA methyltransferase; MGMT; O-6-methylguanine-DNA-alkyltransferase; MGMT;
Gene Name
MGMT
UniProt
P16455
Host
Rabbit
Reactivity
Human, Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human MGMT. AA range:1-50
Clonality
Polyclonal
Applications
WB, IHC, ELISA
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Form
Liquid
Function
Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
Molecular Weight
21646 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Fragment
IgG
Other Gene Names
Methylated-DNA--protein-cysteine methyltransferase
Subcellular Location
Nucleus.
Protein Name
Methylated-DNA--protein-cysteine methyltransferase
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