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Anti-LZK MAP3K13 Antibody

Boster Bio Anti-LZK MAP3K13 Antibody catalog # A09780-1. Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Mitogen-activated protein kinase kinase kinase 13;2.7.11.25; Leucine zipper-bearing kinase; Mixed lineage kinase; MLK; MAP3K13

Gene Name

MAP3K13

UniProt

O43283

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

The antiserum was produced against synthesized peptide derived from human M3K13. AA range:151-200

Clonality

Polyclonal

Tissue Specificity

Expressed in the adult brain, liver, placenta and pancreas, with expression strongest in the pancreas.

Applications

WB, IHC, ELISA

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Form

Liquid

Function

Activates the JUN N-terminal pathway through activation of the MAP kinase kinase MAP2K7. Acts synergistically with PRDX3 to regulate the activation of NF-kappa-B in the cytosol. This activation is kinase-dependent and involves activating the IKK complex, the IKBKB-containing complex that phosphorylates inhibitors of NF-kappa-B.

Molecular Weight

108296 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Fragment

IgG

Other Gene Names

Mitogen-activated protein kinase kinase kinase 13

Subcellular Location

Cytoplasm

Protein Name

Mitogen-activated protein kinase kinase kinase 13

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