What is the catalog number for Anti-Integrin beta ITGB4 Antibody?

The catalog number for Anti-Integrin beta ITGB4 Antibody is A01015-1.

What sizes are available for Anti-Integrin beta ITGB4 Antibody?

Anti-Integrin beta ITGB4 Antibody is available in the following size(s): 100 µL.

Is Anti-Integrin beta ITGB4 Antibody in stock?

Anti-Integrin beta ITGB4 Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-Integrin beta ITGB4 Antibody?

The safety data sheet for Anti-Integrin beta ITGB4 Antibody is available here: https://www.bosterbio.com/msds?sku=A01015-1.

Anti-Integrin beta ITGB4 Antibody

Boster Bio Anti-Integrin beta ITGB4 Antibody catalog # A01015-1. Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Integrin beta-4; GP150; CD104; ITGB4;

Gene Name

ITGB4

UniProt

P16144

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

The antiserum was produced against synthesized peptide derived from human Integrin beta4. AA range:1481-1530

Clonality

Polyclonal

Tissue Specificity

Integrin alpha-6/beta-4 is predominantly expressed by epithelia. Isoform beta-4D is also expressed in colon and placenta. Isoform beta-4E is also expressed in epidermis, lung, duodenum, heart, spleen and stomach.

Applications

WB, IHC, ELISA

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Form

Liquid

Function

Integrin alpha-6/beta-4 is a receptor for laminin. Plays a critical structural role in the hemidesmosome of epithelial cells. Is required for the regulation of keratinocyte polarity and motility. ITGA6:ITGB4 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling (PubMed:20682778) . ITGA6:ITGB4 binds to IGF1 and this binding is essential for IGF1 signaling (PubMed:22351760) . ITGA6:ITGB4 binds to IGF2 and this binding is essential for IGF2 signaling (PubMed:28873464) .

Molecular Weight

202167 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Fragment

IgG

Other Gene Names

Integrin beta-4

Subcellular Location

Cell membrane; Single-pass type I membrane protein. Cell membrane; Lipid-anchor. Cell junction, hemidesmosome. Colocalizes with DST at the leading edge of migrating keratinocytes.