Anti-IL-11 Antibody
Boster Bio Anti-IL-11 Antibody catalog # A01160-3. Tested in ELISA, IHC applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
Interleukin-11; IL-11; Adipogenesis inhibitory factor
Gene Name
IL11
UniProt
P20809
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human IL-11. AA range:27-76
Clonality
Polyclonal
Applications
IHC, ELISA
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Form
Liquid
Function
Cytokine that stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells and induces megakaryocyte maturation resulting in increased platelet production (PubMed:2145578) . Also promotes the proliferation of hepatocytes in response to liver damage. Binding to its receptor formed by IL6ST and either IL11RA1 or IL11RA2 activates a signaling cascade that promotes cell proliferation (PubMed:12919066) . Signaling leads to the activation of intracellular protein kinases and the phosphorylation of STAT3.
Molecular Weight
21429 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Fragment
IgG
Other Gene Names
Interleukin-11
Subcellular Location
Secreted
Protein Name
Interleukin-11
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